The Preventive Cardiology Program at UMDNJ-New Jersey Medical School is
conducting a research study called ExCel, sponsored by the National Cancer Institute of Canada Clinical Trials Group. The goal of the study is to evaluate the effect of Exemestane, an FDA approved drug, on women at increased risk for breast
cancer. Factors that could increase the risk of developing breast cancer are age, family history, age at first menstrual cycle and age at the time of first child’s birth. To be eligible to participate, women must be postmenopausal — age 35 or older if surgical menopause – and at increased risk for developing breast cancer. Participants will receive study-related medical exams, including mammogram and bone mineral density test, and study medication. All study visits will be conducted in the Doctor’s Office Center (DOC), 90 Bergen Street, Suite 4200 in Newark.

Norman L. Lasser, MD, PhD, FAHA, director of the Preventive Cardiology Program, is the principal investigator. For more information call Roberta Silverberg at 973-972-6107.

Pre-diabetes Research Study

The Institute for Nutrition Interventions at UMDNJ’s School of Health Related Professions and the Division of Endocrinology at UMDNJ-New Jersey Medical School are doing a 16-week randomized research trial for individuals with pre-diabetes. The goal of the study is to evaluate whether almond consumption will lower the risk of developing Type II diabetes. Volunteers who are older than age 18, are proficient in English and have pre-diabetes (fasting blood glucose between 100 and 125 mg/dl or casual blood glucose Ž 140-199 mg/dl) and a BMI of 20-35 kg/m2 may be eligible to participate in the study. Participants will receive study-related exams, blood work, body composition tests, nutrition counseling, stipend and travel compensation. Study visits will be conducted at the University of Medicine and Dentistry of New Jersey’s Newark campus.

For more information call Michelle Wien, DrPH, RD, principal investigator, at 973-972-9487 or David Bleich, MD, at 973-972-6170.

Alcohol Dependence

Adolescents between the ages of 12 and 17 are needed to participate in a 12-week clinical drug study on alcohol dependence at UMDNJ-Robert Wood Johnson Medical School, Division of Child and Adolescent Psychiatry in Piscataway. The purpose of the study is to explore treatment options for patients with alcohol dependence. To be
eligible, participants must have a diagnosis of alcohol dependence and they must be willing to undergo an interview.

Theodore Petti, MD, MPH, is the principal investigator. For more information call Kurt Bopp, clinical research coordinator, at 973-235-5690.

Childhood Autism

The Division of Child and Adolescent Psychiatry at UMDNJ-Robert Wood Johnson Medical School in Piscataway is conducting two (an 8-week and a 12-week) clinical drug studies on autism. The goal of the studies is to explore treatment options for children between the ages of 5 and 17 with autism. To be eligible, participants must have a diagnosis of autism and they must be willing to undergo an interview. The interview and questionnaires may take four hours to complete. The interview can be completed at the second visit if necessary. Medication will be provided at no cost. Those who qualify will be closely monitored by the study doctor.

Sherie Novotny, MD, is the principal investigator. Contact Kurt Bopp, clinical research coordinator, at 732-235-5690.

ADHD Study

Children between the ages of 6 and 12 are needed to participate in a five-week clinical drug study on Attention Deficit Hyperactivity Disorder (ADHD) at UMDNJ-Robert Wood Johnson Medical School, Division of Child and Adolescent Psychiatry, in Piscataway. To qualify, volunteers must have a diagnosis of ADHD and they must be willing to undergo an interview.

Theodore Petti, MD, MPH, is the principal investigator. For additional information call Kurt Bopp, clinical research coordinator, at 732-235-5690.

Bipolar Disorder

A research study of an investigational medication for children and adolescents between the ages of 10 and 17 is being conducted in the Division of Child and Adolescent Psychiatry at UMDNJ-Robert Wood Johnson Medical School in Piscataway. To be eligible to participate, volunteers must have been diagnosed with bipolar disorder (manic depressive illness). In addition, they have experienced some or all of the following symptoms: extreme shifts in energy, mood, or behavior (mood swings); difficulty functioning in school, with friends or at home; sleep changes; impulsivity; excessive irritability; and inability or reduced ability to concentrate.
Participants will receive medical and psychological evaluations, treatment, investigational medication and close medical supervision at no cost.

Theodore Petti, MD, MPH, is the principal investigator. For more information contact Kurt Bopp at 732-235-5690.

Depression in Children

Children between the ages of 12 and 17 are needed to participate in an 11-week clinical drug study on major depressive disorder (MDD) at UMDNJ-Robert Wood Johnson Medical School, Division of Child and Adolescent Psychiatry in Piscataway. The purpose of the study is to explore options for patients with MDD. To be eligible, participants must have a diagnosis of MDD or be experiencing symptoms which can include sadness, irritability, loss of energy, lack of concentration and feelings of worthlessness.

Theodore Petti, MD, MPH, is the principal investigator. For more information call Kurt Bopp, clinical research coordinator, at 732-235-5690.

Quit Smoking

Smokers age 18 or older are needed to participate in a clinical study to stop smoking. Volunteers who suffer from cancer, heart disease, lung disease, diabetes, high blood pressure or cholesterol, circulation problems, cataracts, acid reflux, ulcers, osteoporosis, abnormal Pap tests or erectile dysfunction may be eligible to participate in the study. All medications are FDA approved and will be provided at no cost.

Michael Steinberg, MD, MPH, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, is the principal investigator. For more
information call 732-235-7149.

Discuss Your Smoking

Smokers age 18 or older are needed for a study being conducted at UMDNJ-Robert Wood Johnson Medical School in New Brunswick. Volunteers must have one or more of the following conditions: cancer, heart disease, lung disease,
diabetes, high blood pressure or cholesterol, circulation problems, cataracts, acid reflux, ulcers, osteoporosis, abnormal Pap tests or erectile dysfunction. Volunteers do not need to want to quit smoking, but should be willing to discuss their smoking. Participants will be asked to meet for one hour and have a 20-minute telephone follow-up. Upon completion of the study, they will receive a $25 gift card.

Michael Steinberg, MD, MPH, RWJMS, New Brunswick, is the principal investigator. For more information call 732-235-7149.

Postmenopausal Women

The Women’s Health Institute at UMDNJ-Robert Wood Johnson Medical School in New Brunswick is looking for female volunteers between the ages of 45 and 80 who are experiencing vaginal dryness, itching, burning or painful intercourse to participate in a study for the treatment of moderate to severe vulvar/vaginal atrophy in postmenopausal women. To be eligible to participate, volunteers must be postmenopausal and in good health with their uterus intact; and have had their natural menstrual cycle completed at least 12 months ago. Those who qualify will receive all study related tests, exams and medication at no cost. Participants will be
compensated $306.26 upon completion of the study.

Gloria Bachmann, MD, is the principal investigator. For more information call or email the study coordinator, Diane Brevet, at 732-235-7799, brevetdi@umdnj.edu. All calls are confidential.

Memory and Multiple Sclerosis

Kessler Medical Rehabilitation Research and Education Corporation in West Orange is looking for volunteers to participate in a research study on working memory in individuals with multiple sclerosis. To be eligible for participation in the study, participants must: have been diagnosed with multiple sclerosis; be between the ages of 18 and 55; not pregnant; and not have other neurological illness. Volunteers will be required to participate in a two-to-three hour visit to Kessler Rehabilitation Research and Education Corporation in West Orange for paper-and-pencil tests and questionnaires; and a one-hour visit to the University of Medicine and Dentistry of New Jersey in Newark for a functional MRI. Upon completion of the study, participants will be compensated.

The principal investigator for the study is Nancy D. Chiaravalloti, PhD. For additional information call Nancy B. Moore, research coordinator, at 973-530-3660. n n

Clinical Trials Call for volunteers

Clinical Trials
Call for volunteers