call for volunteers
Osteoporosis Study for Women
Volunteers are needed to participate in an osteoporosis study for women age 65 and older at UMDNJ-Robert Wood Johnson Medical School in New Brunswick. The study will evaluate the effect of a designer estrogen called Levormeloxifene on the cardiovascular system and the bones, and its ability to lower cholesterol and prevent heart disease. Levormeloxifene is a new class of drug that strengthens thinning, fragile bones and reduces bone loss. The drug is designed to perform like estrogen without stimulating breast or uterine tissue. Women who have used prescription medicines for the treatment of osteoporosis in the last six to 12 months or who have had a stroke, breast cancer or endometrial cancer are not eligible to participate. Volunteers are required to take oral medication daily for the length of the study. The participants' vital statistics and overall physical and psychological health will be closely monitored. Nine visits within the first three years of the five-year study are required. Travel expenses will be reimbursed. For more information or to volunteer, call the Women's Health Research Section at 732-235-7353.
Psychopharmacologists at UMDNJ-Robert Wood Johnson Medical School in Piscataway are seeking volunteers to participate in a study of a new formulation of an already approved medication for the treatment of persistent anxiety. Volunteers age 18 and older who suffer from symptoms of nervousness, tension, irritability, insomnia and similar symptoms of anxiety are eligible to participate. Participants will be paid $50 for each completed visit during the six-week study. All related clinic visits will be free of charge. For more information contact Lesley Allen, PhD, at 732-235-4796. The investigator for this study is Robert Hamer, PhD.
Investigational Drug Studies
Volunteers are being sought for testing of new medications for the treatment of a variety of psychiatric disorders at UMDNJ-Robert Wood Johnson Medical School in Piscataway. Participants will receive free study medications and will be compensated for the completion of visits. All study related testing is done at no cost to the patients. The number of visits required depends on the study. For further information contact the research coordinator, Allison Dicke, at 732-235-5886. The investigators for these studies are Matthew Menza, MD, and Robert Hamer, PhD.
The Clinical Research Center at UMDNJ-Robert Wood Johnson Medical School in New Brunswick is seeking volunteers with psoriasis to participate in research studies being conducted at the school. Eligible participants will be provided physical examinations by board-certified dermatologists, laboratory tests and medication at no cost. Some programs have monetary compensation. Call 732-418-8474 for more information.
New Medication for High Blood Pressure and Diabetic
Hypertension specialists at UMDNJ-Robert Wood Johnson Medical School in New Brunswick are conducting a three-year study to evaluate the effect of a new investigational medication for diabetic kidney disease for individuals with early kidney dysfunction and Type II, adult onset diabetes. Those eligible to participate must be between the ages of 30 and 70, have Type II diabetes, high blood pressure and protein in the urine. Participants will receive free clinic visits, blood pressure medication, laboratory tests and parking. For more information contact Noreen Bradley, RN, at 732-235-7825.
Individuals with hypertension who are at least age 55 are needed to participate in an international study being conducted in the Department of Medicine at Cooper Hospital/University Medical Center in Camden and the Section of Hypertension at UMDNJ-Robert Wood Johnson Medical School in New Brunswick. It will compare the effectiveness of Covera-HS, a calcium channel blocker in a new time-release form, with either atenolol or HCTZ. This study is known as CONVINCE, for controlled onset verapamil investigation of cardiovascular endpoints. Volunteers must have one or more of the 10 defined cardiovascular risk factors, such as a smoking habit, high-risk blood lipid profile or history of heart attack. Those eligible to participate will receive free blood pressure medication for up to six years. For more information on the study being conducted in Camden, contact Lynn Helmer, MD, at 609-342-2489 or Patricia Niblack, MLT, at 609-968-7269. For information on the New Brunswick study, call Noreen Bradley, RN, at 732-235-7825.
Facial Pain Study
Researchers at the UMDNJ-New Jersey Dental School in Newark are seeking women between the ages of 18 and 65 who suffer from facial pain (TMJ) or temporomandibular disorders (TMD). The purpose of the study is to determine the causes of facial pain and the appropriate treatment. Volunteers must never have used oral appliances or bite plates for treatment. Participants are required to complete daily questionnaires at home for two weeks before undergoing a free six-week treatment program. They will receive compensation of $300 upon completion of the study. Women between 18 and 65 years of age without facial pain are also needed for this research project. They will be asked to complete daily questionnaires at home for two weeks and will be paid $100 when the study is completed. The project is directed by Karen Raphael, PhD, and Joseph Marbach, DDS. For further information call the project coordinator, Margaret Spier, at 973-972-8043.
Comprehensive Breast and Cervical Cancer Screening
The Women's Wellness Center in Newark is offering a comprehensive breast and cervical cancer screening program for 500 women over age 50 who live in Essex County. Services include Pap tests, mammograms and breast self-exam teaching. To be eligible, a woman must be at least 50 years old, reside in Essex county, meet income eligibility guidelines and have limited or no health insurance. House calls are made to single locations such as apartment buildings, churches or senior centers for groups of 15 or more women who qualify. Portable mammography is available to provide service on site. For further information on the study, contact the Women's Wellness Center at 973-972-2777.
Women with Spinal Cord Injuries and Able-bodied Women
are Sought for Sexual Response Study
Kessler Institute for Rehabilitation in West Orange is conducting a study to learn how spinal cord injuries affect female sexual function and to test new methods to improve sexual satisfaction. Able-bodied women and those with SCI at or below the level of T6 are being sought to participate. Those who complete the study will receive compensation for travel expenses and an honorarium of $500. For more information write to Kessler Institute for Rehabilitation, 1199 Pleasant Valley Way, West Orange, NJ 07052, or call research assistant Marie Dziekan, MA, at 800-248-3221, extension 2711.
Brain Injury Research Study
The Research Department at Kessler Rehabilitation Research Corporation in West Orange is conducting a study to evaluate the effectiveness of a non-invasive procedure called Neural Organization Technique (NOT) on cognitive difficulties resulting from traumatic brain injury. The study is based on the principles of chiropractic and acupressure and involves light pressure on various points of the body. Individuals who experienced a brain injury at least 12 months ago and who are currently experiencing cognitive difficulties associated with memory, attention, concentration or problem-solving are sought to participate. Volunteers will receive six weeks of treatments and undergo four assessment sessions at no charge. Participants must reside within driving distance from Kessler. For further information call research associate Diane Zeitlin at 973-731-3900, extension 2064.
Chronic Shoulder Pain in Manual Wheelchair Users with
A study is being conducted in the Research Department at Kessler Institute for Rehabilitation in West Orange on the use of acupuncture and Trager psychophysical integration (a form of massage therapy) in the treatment of chronic shoulder pain in people with spinal cord injuries who use manual wheelchairs. Spinal cord injured individuals, age 18 and older, who are currently experiencing shoulder pain that has persisted for at least three months and who use manual wheelchairs, are being sought to participate in a 15-week study. Following five weeks of in-house monitoring of shoulder pain levels, participants will receive five weeks of acupuncture or five weeks of Trager psychophysical integration. During this phase, 10 acupuncture or 10 Trager treatments will be given at no cost to the participants. Those who participate in the study will receive $175. Screening for entrance into the study will take place at the Kessler Institute for Rehabilitation facility in West Orange. For more information call Trevor Dyson-Hudson, MD, at 800-248-3221, extension 2259 or 800-648-0296.
For Women Only
The Department of Obstetrics and Gynecology at UMDNJ-New Jersey Medical School in Newark is looking for women between the ages of 18 and 38 to participate in a brief study, lasting through two and one-half menstrual cycles. Participants will be required to collect their urine at home for six weeks, have two endometrial aspirations - a sampling of a thin piece of tissue from the uterine lining - and agree to use birth control (not oral contraceptives) while participating in the study. The purpose of the study is to examine the lining of the uterus in normal cycling women. Volunteers are required to complete two office visits at no cost and will be compensated $335 upon completion. For more information call Cheryl Forst, RN, BSN, at 973-972-6573.
Women ages 18 through 40 are being sought to participate in a study to assess the ability of contraceptive vaginal rings to prevent pregnancy, control menstrual cycles and minimize hormonal side effects. Each participant will wear a vaginal ring continuously for three weeks and remove it during menstruation. After menstruation, the volunteer will wear a vaginal ring for an additional three weeks and this process will be repeated for 13 menstrual cycles. During the study, participants will receive five examinations and one post-treatment evaluation. The study will be conducted at UMDNJ-Robert Wood Johnson Medical School in New Brunswick. To volunteer or to obtain more information, call the Women's Health Research Section at 732-235-7353.
The Southern New Jersey AIDS Clinical Trials Unit is seeking volunteers to participate in clinical trials to determine whether patients with HIV infection, who have experienced significant recovery of their absolute CD4+ cell count following active antiretroviral therapy, should receive treatment to prevent Mycobacterium Avium Complex (MAC) and bacterial pneumonia. Patients must have a history of a CD4+ cell count that is less than 50 cells/mm3 any time in the past and a current CD4+ cell count of greater than 100cells/mm3. For more information on the treatment of HIV and other studies call: Cooper Hospital/University Medical Center in Camden at 609-963-6890; Garden State Infectious Disease in Voorhees at 609-566-3190; Jersey Shore Medical Center in Neptune at 908-776-4709 or Mercer Area Early Intervention Services in Trenton at 609-538-0025.
Stroke Prevention Study
Focuses on African-Americans The National Institutes of Health is sponsoring the first nationwide study on stroke prevention specifically in African-Americans. The goal of the study is to compare two commonly-used clot-preventing medications, aspirin and Ticlid, to measure their effectiveness in the prevention of stroke. Researchers are in need of 1,200 patients to participate in 20 study centers across the country. To be eligible, participants must be African-Americans and have had a stroke within the last 90 days. For more information or to enroll in the study, call the National Stroke Association toll-free at 1-800-STROKES. New Jersey residents can call UMDNJ-New Jersey Medical School in Newark at 973-972-0571.
Clinical researchers in the Department of Medicine at UMDNJ-Robert Wood Johnson Medical School in New Brunswick are seeking volunteers age 18 and older to participate in an investigational drug study. The study will measure the effectiveness of the drug Lescol, in a slow release formulation to lower blood cholesterol and the risk of heart disease. Those eligible to participate will receive free physical examinations, study medications and relevant laboratory tests. For more information contact Shelley Greenhaus, RN, at 732-235-7751.
Osteoporosis and Paget's Disease Studies
Volunteers are being sought to participate in studies being conducted at UMDNJ-Robert Wood Johnson Medical School in New Brunswick. One of the studies will compare the efficacy of Fosamax once or twice weekly versus once daily in the prevention and treatment of osteoporosis. To be eligible to participate in the study, volunteers must be age 40 and older, at least six months post-menopausal and in generally good health. Free x-rays, bone density measurements and study drug will be provided. A second study being conducted at the school is in need of volunteers to participate in a new oral drug study for the treatment of Paget's Disease of the bones. The study requires hospitalization for three-day and seven-day periods. A monetary compensation of $3,000 will be provided to those eligible to participate. For further details and to find out if you qualify for both studies, call Shelley Greenhaus, RN, in the Division of Endocrinology at 732-235-7751.
Impacted Wisdom Tooth Study
Volunteers are needed for an analgesic study involving impacted wisdom teeth that is being conducted at UMDNJ-New Jersey Dental School in the Oral/Maxillofacial Surgery department and in the Dental Medicine department at UMDNJ-University Hospital in Newark. A new pain medication is being tested for its effectiveness after oral surgery. Volunteers are required to complete questionnaires assessing their relief during a 24-hour period. Blood sampling will be necessary before and after surgery. A brief postoperative visit is routinely done a week later and monetary compensation is available to eligible participants. For further information call Fran Devonshire, RN, at 973-972-4777.
The Women's Health Research Section at UMDNJ-Robert Wood Johnson Medical School in New Brunswick is looking for women between the ages of 18 and 45, in good health and who meet entry criteria, to participate in a study evaluating the effects of a new method of contraception. The study, lasting either six or 12 months, will provide free physical examinations, Pap smears and laboratory tests. Volunteers will receive up to $150 for completing the study. For further details and to find out if you meet entry criteria, call Pat Agolio or Mitzi Dolese, RNC, at 732-235-7353 or 732-235-7925 between 9 am and 5 pm, Monday through Friday.
Non-hormonal Vaginal Cream
The Women's Health Research Section at UMDNJ-Robert Wood Johnson Medical School in New Brunswick is looking for volunteers to participate in a non-hormonal vaginal cream study for sexual arousal disorders. Volunteers must be pre-menopausal, have regular menstrual cycles and at be least 21 years old. Compensation will be provided during the five- to seven-week study. For more information call Pat Agolio or Mitzi Dolese, RNC, at 732-235-7353 or 732-235-7925 between 9 am and 5 pm, Monday through Friday.
Seizures in the Elderly
The Department of Neurology, in conjunction with the Veterans Administration, is conducting a five-year study to evaluate antiepileptic drugs (AEDs) in the elderly population. The purpose of the study is to determine which AED may provide the most effective treatment with the fewest side effects. To be eligible, volunteers must be age 65 and older, US veterans, and have had a recent onset of spontaneous epileptic seizures. Participants will receive free clinic visits, seizure medication, laboratory tests and parking. For further information call Tricia Seuffert, RN, at 732-235-7728 or David M. Treiman, MD, at 732-235-7732.
Spring - Summer 1998 Table of Contents