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Special Issue: Trauma Fall 2004

Message from the President


Over the past five years, UMDNJ has emerged as a powerhouse of biomedical research, ranking in the top 80 academic research institutions in the nation and securing more than $521 million in federal funding, one of the most significant rates of growth of any research university in the country. With a capital construction program that has doubled research space and an active recruitment program targeting scientists with federal funding of at least $1 million each, we fully expect to maintain a research growth trajectory.

We are in the process of establishing a President’s Strategic Council on Research Advancement to provide us with information and perspectives on basic and translational research in order to maximize the wealth of expertise and resources throughout UMDNJ. The Council’s first priorities will be our neuroscience and stem cell initiatives. The membership will include UMDNJ faculty and community representatives as well as partners from other institutions.

As part of our academic and research missions, UMDNJ is positioning itself to enhance collaborations with the state’s pharmaceutical and biotechnology industries. Just recently the University and Medco Health Solutions, Inc. unveiled plans to develop the Medco “Institute at UMDNJ for Drug Safety, Policy and Epidemiology” at the UMDNJ-School of Public Health. The Institute will develop research protocols and programs focused on epidemiology, drug safety and quality, pharmaceutical cost containment, medication insurance coverage, use of pharmaceuticals in vulnerable populations and trends in drug management. The first project will examine the potential association between the use of anti-psychotic medications and the risk of developing diabetes.

This initiative joins two other collaborative programs with pharmaceutical companies. Two years ago University Behavioral HealthCare and Eli Lilly and Company announced a new Center for Excellence in Psychiatry, which focuses on training behavioral healthcare providers nationwide in new treatment approaches to improve the care of individuals who suffer from severe and persistent mental illness. Last August, the Aventis Pharmaceuticals Foundation and UMDNJ-New Jersey Medical School established the Aventis Pediatric Asthma Center, to focus on asthma care and prevention for children, research and community education.

As you will see in this issue, our partnerships with pharmaceutical companies have yielded much research activity. We look forward to continuing productive ongoing partnerships and developing new collaborations.


Contents


Message from the President
John J. Petillo, PhD,
President

UMDNJ's clinical research enterprise
Roy S. Chaleff, PhD,
Acting Vice President for Research and Editor

New drugs, devices and other developments in cardiovascular disease
by John B. Kostis

Developing new therapies for the treatment of heart failure
by Marc Klapholz

Advancing oral health through industry/ academic partnerships
by Daniel Fine

Transabdominal fetal pulse oximetry using near-infrared spectroscopy
by Anthony M. Vintzileos

Clinical trials at the Center for Aging
by Anita Chopra and Thomas A. Cavalieri

New insights, new strategies, new treatments for psoriasis
by Alice B. Gottlieb

Inhaled insulin therapy in the treatment of diabetes
by Stephen H. Schneider

Comparison of three treatment alternatives for Raynaud's phenomenon
by Leonard Bielory

Antidepressant shows promise in the treatment of fibromyalgia
by Stephen Burnstein

Cognitive enhancers to improve complications of Alzheimer's disease
by Peter M. Aupperle

Putting complementary and alternative medicine under the microscope
by Adam Perlman

Finding a cure for cancer starts with phase I trials
by Eric H. Rubin

Volume t, Number2 Fall 2004 email research@umdnj.edu