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Intraoperative
MRI
This
method allows the surgeon to obtain actual MRI images
in the operating room before, during, and after surgery.
We were the first institution in North America and only
the second in the world to use the innovative Pole Star
N-10 intraoperative MRI system, developed by Odin
Medical Technologies in Israel.
This
system also includes a surgical navigation tool which
actually has a link to our own surgical navigation lowered
down on the page, kind of thus providing a complete
system for intraoperative imaging and guidance for brain
surgery.

Intraoperative
MRI allows the surgeon to monitor the progress of a
procedure, for instance tumor removal. The possibility
of a surgical cure is increased as no surprises are
left for MRI scan done the day after surgery, as in
the past. The potential dangers of brain shift, whereby
during surgery the brain can move and render inaccurate
coordinates obtained from preoperative imaging, is overcome
by the freshening of images obtained during surgery.
For
image guided surgery we were the first to describe the
method whereby via intraoperative MRI, a non-invasive
way to map critical brain areas (such as those responsible
for movement, sensation, vision, and speech) can be
mapped on to a computer in the operating room. Using
surgical navigation again that link, we can precisely
map out in the operating room not just the location
of a lesion, such as a tumor but also the most critical
areas of the brain that must be avoided during surgery.
Our
functional imaging laboratory , also develops ways
of mapping, not just the surface of the brain, but the
critical pathways known as white matter that connect
the brain to other parts of the body.
We also reported the first series of incorporation
of functional MRI for stereotactic radiosurgery. Thus
we can ploy functional image guidance not just for open
surgery, but for non-invasive treatment of a variety
of intracranial lesions.
The
Department of Radiology at NJ Medical School in
conjunction with our neighbors at Rutgers University
in Newark have formed whatever is called Center for
Advanced Imaging. Included here are a cutting edge three
Tesla MRI scanner that will allow us to obtain brain
images of unparalleled quality as well as to perform
functional MRI for non-invasive brain mapping with greater
speed and detail than ever before. A cutting edge CT-PET
scanner will provide yet another means of obtaining
functional imaging of the brain. A dedicated team of
Radiologists and MR Physicists work to incorporate these
methods and develop, with us, ways of bringing a full
benefit into the neurosurgical operating room.
Stereotactic
Radiosurgery
Stereotactic Radiosurgery is a method of treating lesions
in the brain and at the skull base, with a highly concentrated
dose of x-rays, by aiming radiation beams only at the
target and not the surrounding brain, a very powerful
dose can be delivered while making a risk of complications
minimal. We use the latest Radiosurgical planning system
developed by Radionics Incorporated, known as X-Knife
RT. We have two linear accelerators litigated to the
use of Radiosurgery. We have had our links here to publications
as well. We have described work incorporating functional
imaging into the Radiosurgical treatment planning. As
a result we cannot only target the area of interest,
but avoid radiation to critical parts of the brain.
SRS is used to treat patients with a large variety of
conditions, including gliomas, meningiomas, acoustic
neuromas, other schwannomas, trigeminal neuralgia, and
arterial venous malformations. As part of our Radiosurgery
Program we have established a multi-center trial to
evaluate an aggressive treatment program aimed at patients
with primary brain tumors. Individuals entered into
the study will undergo surgery with removal of the tumor,
implantation of Gliadel link, chemotherapy wafers, Fractionated
radiotherapy, and stereotactic radiosurgery as part
of up front treatment.
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Surgical
Navigation
Certain patients with brain tumors are not eligible
for intraoperative MRI guided surgery. This may include,
for instance, patients with pacemakers who cannot
undergo any sort of MRI scanning safely. As part of
a close working relationship with Medtronic Inc.,
we have two state of the art Stealth stations. This
is the innovative device developed by Surgical Navigation
Technologies, a division of Medtronic. This tool in-
corporates preoperative images, including MRI, CT,
and functional imaging studies into the computers
in the operating room. A hand held probe linked to
the computer can be used to point anywhere on the
patients head or brain, with the corresponding area
shown with great accuracy on a computer screen. Thus,
there is no need to guess at the relationship between
an area on or in the brain, inspected by sight and
where that corresponds to the patient's preoperative
images. In many cases with a border between a lesion,
the normal brain is indistinct, this information is
invaluable. The Pole-Star N-10 Intraoperative MRI
unit also includes an intergrated surgical navigation
system that is used in surgery and know that we should
link to that above.
The
patients undergoing spine surgery may benefit from
image-guidance with the stealth station. In particular,
use of navigation techniques can help the more precise
placement of instruments into the spine. These metal
tools are often of help in maximizing the results
of spinal surgery so that patients can return to independent
activity as quickly as possible.
Movement Disorder Surgery
Patients
with a variety of movements disorders, (including
Parkinson's, central trauma, Multiple Sclerosis related
tremor, and Distonia) may benefit from image guided
surgery. If they have failed, the best possible medical
therapy, as determined by expert neurological care,
in creation of a small hole or lesion, or insertion
of a deep brain stimulator. Using a stereotactic fling
with the aide of MRI and CT scans, a treatment plan
is created on the stealth station link computer. A
small probe is inserted to an area in the center of
the brain, depending on what type of movement is being
treated, and a current is passed through. Testing
the patient confirms that the abnormal movement is
eliminated while side effects are avoided. While some
patients can still benefit from creation of a lesion,
the advantages of DBS insertion include the ability
to adjust the affect of the device as well as the
fewer complications with this method.
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