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Andrew
R. Pachner, MD
Speciality Areas:
Education:
Medical School: Yale University School of Medicine, 1971-1975; M.D.thesis- the role of cAMP in lymphocyte transformation
Residencies:
Johns Hopkins Hospital, Internship and Assistant Residency, Internal Medicine, 1975-1977 Yale-New Haven Hospital, Fellowship and Chief Residency, Neurology,
1977-1980
Research interests: neuroimmunology and neuro-infectious diseases, particularly Lyme neuroborreliosis,
myasthenia gravis, and multiple sclerosis, experimental models of neuroimmunological
disease particularly myasthenia gravis and Lyme neuroborreliosis; production
and role of antibody in disease.
Grant Support:
Principal Investigator: The pathogenesis of neuroborreliosis: a molecular
analysis, (RO1)-National Institutes of Health/National Institute of Neurological
Disorders
Principal Investigator: Non-Human Primate Animal Models for Experimental
Research on Chronic Lyme Neuroborreliosis (NIH Contract)-National Institutes
of Health/National Institute of Allergy and Infectious Diseases.
Selected Articles:
Pachner, A.R. and Simon, R.P., Monkey business: CNS infections that
won’t go away, Neurology, 51:935-937, 1998
Pachner, A.R. Zhang, W.F. Schaefer, H., Schaefer, S., O'Neill T., Detection
of active infection in nonhuman primates with Lyme neuroborreliosis: comparison
of PCR, culture, and a bioassay. J Clin Microbiol 36: 3243-7, 1998
Pachner, A.R. Zhang, W.F. Schaefer, H., Schaefer, S., O'Neill T., Detection
of active infection in nonhuman primates with Lyme neuroborreliosis: comparison
of PCR, culture, and a bioassay. J Clin Microbiol 36: 3243-7, 1998
Amemiya, K., Schaefer, H., Pachner, A.R. Isolation of DNA after extraction
of RNA to detect the presence of Borrelia burgdorferi and expression of
host cellular genes from the same tissue sample. J Clin Microbiol. 37:2087-9,
1999
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