Center for BioDefense - Research

Bioterrorism-related projects ongoing at the Center for BioDefense and NJMS/RWJMS:

1. “Use of DNA Microarrays to Identify Diagnostic Signature Transcriptional Profiles for Host Responses to Infectious Agents.” 2000-2001, $1.3m. Jerrold Ellner, M.D. Principal Investigator. Coinvestigators: P. P. Tolias, N. Connell, E. Raveche, D. Hom, R. Wallis, P. Soteropoulos.

2. “Use of DNA Microarrays to Identify Diagnostic Signature Transcriptional Profiles for Host Responses to Infectious Agents: Viral Pathogens.”, 2001-2002, $1.7m. Jerrold Ellner, M.D. Principal Investigator. Coinvestigators: N. Connell, P. P. Tolias, E. Raveche, D. Hom, I. Behlau, R. Wallis, P. Soteropoulos, S. Kotenko, G. Gallagher, S. Schutzer, J. Langer, V. Stollar.

3. Effects of anthrax lethal toxin on bone marrow development and on neural synaptic activities. Preliminary studies: J. McArdle, P. Rameshwar, N. Connell

4. Regulation of gene expression in Bacillus anthracis. M. Inouye, N. Connell